Just a quick plug for www.mozy.com and their free offering of 2GB of encrypted data backup on new accounts. The latest client release is stable, works well that I've seen under 10.5, and upgrades to the free plan are relatively cheap ($5/month for unlimited backup).
If you sign up using my referral link, we both get an additional 256MB of capacity added to our accounts. Simply follow the referral link, click on "MozyHome" along the top, then the orange "MozyHome Free" link along the left side to get yourself started.
